Author(s):Marcin Mielecki and Bogdan Lesyng. For physicochemical, thermodynamic, transport, spectra, and other property data & information, the followings are available from “Mol-Instincts”, a chemical database based on quantum mechanics: The SMILES string of CINNAMIC ACID is OC(=O)C=Cc1ccccc1, which can be can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the CINNAMIC ACID. A series of cinnamic acid esters and their derivatives were synthesized and evaluated for antifungal activities in vitro against four plant pathogenic fungi by using the mycelium growth rate method. Differential scanning calorimetry showed that 1 undergoes a single fully reversible temperature induced phase transition at around 132/131 K (cooling/heating). It exists as both a cis and a trans isomer, although the latter is more common. Doceri is free in the iTunes app store. Learn more at http://www.doceri.com 709 The 2D chemical structure image of CINNAMIC ACID is also called skeletal formula, which is the standard notation for organic molecules. Cinnamic acid molecular structure isolated on white. Uses advised against Food, drug, pesticide or biocidal product use. MDL number MFCD00004369. Need to identify active compounds in your natural products? Source: Mol-Instincts Chemical Database, Predicted on Quantum. A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. Fluorimetric studies on the binding of 4-(dimethylamino)cinnamic acid with micelles and bovine serum albumin. Beilstein/REAXYS Number 1905952 . This video screencast was created with Doceri on an iPad. Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:27386, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:35697, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton, 147 deg C / 4 mm (350.4434 °C / 760 mmHg). Sorry this one is long. Cinnamic acid structure. It is collected from the oil of cinnamon and is also found in shea butter. trans-Cinnamic acid exists in all living species, ranging from bacteria to humans. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. cis-ferulic acid (CHEBI:76117) has functional parent cis-cinnamic acid (CHEBI:35699) cis-cinnamate (CHEBI:35700) is conjugate base of cis-cinnamic acid (CHEBI:35699) IUPAC Name (2 Z )-3-phenylprop-2-enoic acid Attention was focused on the antifungal activities exhibited against Aspergillus flavus, Aspergillus terreus, and Aspergillus niger. Data compiled as indicated in comments: ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein DH- Eugene S. Domalski and Elizabeth D. Hearing trans-Cinnamic acid ≥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). The radius of the spheres is therefore smaller than the rod lengths in order to provide a clearer view of the atoms and bonds throughout the chemical structure model of CINNAMIC ACID. Molecular Weight 148.16 . Cinnamic acid (CA) and its hydroxy-derivatives are aromatic building blocks whose structural peculiarities (unsaturation, hydroxylic and/or carboxylic groups) have driven them to a prominent position in polymer science. CopyCopied, InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+ Pre-Registration process . Combustible. C&L Inventory A chemical structure of a molecule includes the arrangement of atoms and the chemical bonds that hold the atoms together. A structure-antifungal activity relationship (SAR) study of 22 related cinnamic acid derivatives was carried out. : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. (E)-3-(4-methoxy-3-(3-methylbut-2-enyl)phenyl)acrylic … trans-Cinnamic acid is a sweet, balsam, and cinnamon tasting compound. … The carbon atoms in the chemical structure of CINNAMIC ACID are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough hydrogen atoms to provide … It is a member of styrenes and a member of cinnamic acids. Cinnamic acid is a white crystalline compound this is slightly soluble in … Structure, properties, spectra, suppliers and links for: Cinnamic acid, m-hydroxy-, methyl ester. Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. The carbon atoms in the chemical structure of CINNAMIC ACID are implied to be located at the corner(s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds. 1b), cinnamyl alcohol (Fig. It was first isolated in 1872 by F. Beilstein (of Handbook of Organic Chemistry fame) and A. Kuhlberg. Affiliation:Bioinformatics Laboratory, Mossakowski Medical Research Center, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland. Cinnamic acid is an organic compound with the formula C6H5CHCHCO2H. The molecular formula of CINNAMIC ACID is available in chemical formula page of CINNAMIC ACID, which identifies each constituent element by its chemical symbol and indicates the proportionate number of atoms of each element. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. The CINNAMIC ACID compound may be called differently depending on the various different situations of industrial applications. Articles of trans-Cinnamic acid are included as well. The 3D chemical structure image of CINNAMIC ACID is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them. The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. Basic structure of quinic acid, chlorogenic acid, and typical hydroxycinnamate substituents. 25 matches found for trans-cinnamic acid Advanced Search | Structure Search Sort By Relevance Name ↑ Name ↓ Base Name ↑ Base Name ↓ Formula Weight ↑ Formula Weight ↓ A structure-antifungal activity relationship (SAR) study of 22 related cinnamic acid derivatives was carried out. Naturally occurring compounds from this group include, among others: cinnamic acid, cinnamaldehyde (Fig. Cinnamic acid exists as trans and cis isomers, but the trans form is the one most often found in nature and is the article of commerce. It is obtained from cinnamon bark and balsam resins such as storax. 2005-03-26. [Pubmed: 18754053] The constrained photophysics of intramolecular charge transfer (ICT) probe 4-(Dimethylamino)cinnamic acid (DMACA) was studied in different surfactant systems as well as in … Cinnamic acid. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). 621-82-9 - WBYWAXJHAXSJNI-UHFFFAOYSA-N - Cinnamic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. It is obtained from cinnamon bark and balsam resins such as storax. It is a conjugate acid of a cinnamate. 106.12 g of Benzaldehyde yields Cinnamic Acid = 148.16 g. 10.5 g of Benzaldehyde shall yield Cinnamic Acid = 148. The CINNAMIC ACID molecule contains a total of 19 bond(s) There are 11 non-H bond(s), 8 multiple bond(s), 2 rotatable bond(s), 2 double bond(s), 6 aromatic bond(s), 1 six-membered ring(s), 1 carboxylic acid(s) (aliphatic) and 1 hydroxyl group(s). Trans-3-phenyl-2-propenoic acid (cinnamic acid) derivatives: structure-activity relationship as hepatoprotective agents Medicinal chemistry (Shāriqah (United Arab Emirates)), 2007 Rosa Bobadilla CopyCopied, WBYWAXJHAXSJNI-VOTSOKGWSA-N The CINNAMIC ACID molecule shown in the visualization screen can be rotated interactively by keep clicking and moving the mouse button. Linear Formula C 6 H 5 CH=CHCOOH . Incompatible with strong oxidizing agents. Difference spectra in the FT-Raman amide I band depicted changes in the secondary structure of gluten network modified by five phenolic acids in the content 0.05%, 0.1% and 0.2%: cinnamic acid (CINA), coumaric acid (COUA), caffeic acid (CAFA), ferulic acid (FERA) and chlorogenic acid (CHLA). Almost all of the compounds showed some inhibition activity on each of the fungi at 0.5 mM. Stereoisomers: (Z)-3-Phenyl-2-propenoic acid; 2-Propenoic acid, 3-phenyl- However, relatively little work has been carried out on the angiogenic responses of C. cassia and its active compound cinnamic acid (CA), despite its excellent pharmacological action. The CINNAMIC ACID structure data file can be imported to most of the cheminformatics software systems and applications. The first step has multiple possibilities. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. 621-82-9 - WBYWAXJHAXSJNI-UHFFFAOYSA-N - Cinnamic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. The crystal structure of trans-4-(trifluoromethyl) cinnamic acid (1) has been determined in the triclinic space groupP. The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. 140-10-3 - WBYWAXJHAXSJNI-VOTSOKGWSA-N - Cinnamic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. (trans)-Cinnamic Acid Compound with free spectra: 46 NMR, 14 FTIR, 2 Raman, 2 UV-Vis, and 23 MS Formula: C 9 H 8 O 2; Molecular weight: 148.1586; IUPAC Standard InChI: The molecular weight of CINNAMIC ACID is available in molecular weight page of CINNAMIC ACID, which is calculated as the sum of the atomic weights of each constituent element multiplied by the number of atoms of that element in the molecular formula. Sorry this one is long. This video screencast was created with Doceri on an iPad. … Identification Product Name trans-Cinnamic acid Cat No. By right-clicking the visualization screen, various other options are available including the visualization of van der Waals surface and exporting to a image file. The antioxidant activity of selected representatives of flavonoids, coumarins, and cinnamic acids was examined by measuring their protective action toward linoleic acid peroxidation in micelles of sodium dodecyl sulfate in buffer solution, pH 7.4. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). Molecular Formula C 9 H 8 O 2; Average mass 148.159 Da; Monoisotopic mass 148.052429 Da; ChemSpider ID 392447 α-Cyano-4-hydroxycinnamic acid; Caffeic acid – burdock, hawthorn, artichoke, pear, basil, thyme, oregano, apple Mouse wheel zoom is available as well – the size of the CINNAMIC ACID molecule can be increased or decreased by scrolling the mouse wheel. The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. Download preview. Conversion of complicated chemical-related units is no longer sophisticated with the aid of UnitPot. The information of the atoms, bonds, connectivity and coordinates included in the chemical structure of CINNAMIC ACID can easily be identified by this visualization. Ultraviolet absorption spectra are recorded of cis‐ and trans‐ cinnamic acid, of cis‐ and trans‐1,2,3,4,‐tetrahydronaphthylidene (1) acetic acid and of cis‐ and trans‐β‐(naphthyl‐1) acrylic acid.The cis isomers all show a lower extinction coefficient and a shift of the maximum of absorption to shorter wave‐length in comparison with the trans isomers. Create. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Cis-cinnamic acid is the Z (cis) isomer of cinnamic acid It is a conjugate acid of a cis-cinnamate. Molecular Weight. The crystal structures of p-chloro-trans-cinnamic acid (I) and β-(p-chlorophenyl) propionic acid (II) have been determined from X-ray diffractometer data. These compounds are hydroxy derivatives of cinnamic acid.. Benzoic and cinnamic acid derivatives as antioxidants: structure-activity relation Affiliation:Bioinformatics Laboratory, Mossakowski Medical Research Center, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warsaw, Poland. EC Number 205-398-1. The RCSB PDB also provides a variety of tools and resources. Hydroxycinnamic acids (hydroxycinnamates) are a class of aromatic acids or phenylpropanoids having a C 6 –C 3 skeleton. Bromination of Cinnamic acid Supplementary Material Experimental notes This experiment aims at the preparation of the 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid by bromine addition. 5 / 14. Structure, properties, spectra, suppliers and links for: Cinnamic acid, m-hydroxy-, methyl ester. Doceri is free in the iTunes app store. Beilstein/REAXYS Number 1905952 . Title:Cinnamic Acid Derivatives as Inhibitors of Oncogenic Protein Kinases – Structure, Mechanisms and Biomedical Effects# VOLUME: 23 ISSUE: 10. Images of the chemical structure of CINNAMIC ACID are given below: The 2D chemical structure image of CINNAMIC ACID is also called skeletal formula, which is the standard notation for organic molecules. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. It is found in Cinnamomum cassia. Below are the list of the other names (synonyms) of CINNAMIC ACID including the various registry numbers, if available: Visit ChemTopia for further professional chemical information on the basis of a comprehensive intelligence networking platform for experts in the discipline around the globe. (trans)-Cinnamic Acid Compound with free spectra: 46 NMR, 14 FTIR, 2 Raman, 2 UV-Vis, and 23 MS Active compounds in your natural products contents of this page can freely be shared if cited follows. Many organic solvents in 1872 by F. Beilstein ( of Handbook of cinnamic acid structure Chemistry fame ) and A..... 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